Cargando…

Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones

NADPH oxidase 5 (NOX5) is a transmembrane signaling enzyme that produces superoxide in response to elevated cytosolic calcium. In addition to its association with numerous human diseases, NOX5 has recently been discovered to play crucial roles in the immune response and cardiovascular system. Detail...

Descripción completa

Detalles Bibliográficos
Autores principales: Sweeny, Elizabeth A., Schlanger, Simon, Stuehr, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394750/
https://www.ncbi.nlm.nih.gov/pubmed/32738790
http://dx.doi.org/10.1016/j.redox.2020.101656