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Dynamic regulation of NADPH oxidase 5 by intracellular heme levels and cellular chaperones
NADPH oxidase 5 (NOX5) is a transmembrane signaling enzyme that produces superoxide in response to elevated cytosolic calcium. In addition to its association with numerous human diseases, NOX5 has recently been discovered to play crucial roles in the immune response and cardiovascular system. Detail...
Autores principales: | Sweeny, Elizabeth A., Schlanger, Simon, Stuehr, Dennis J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394750/ https://www.ncbi.nlm.nih.gov/pubmed/32738790 http://dx.doi.org/10.1016/j.redox.2020.101656 |
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