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Overexpression of serotonin receptor 5b expression rescues neuronal and behavioral deficits in a mouse model of Kabuki syndrome

5-hydroxytryptamine receptor 5B (5-HT5B) is a gene coding for a G protein-coupled receptor (GPCR) that plays key roles in several neurodevelopmental disorders. Our previous study showed that disruption of 5-HT5B induced by lysine (K)-specific demethylase 6A (Kdm6a, also known as Utx) conditional kno...

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Detalles Bibliográficos
Autores principales: Tang, Gang-Bin, Mi, Ting-Wei, Sun, Man-Lian, Xu, Ya-Jie, Yang, Shu-Guang, Du, Hong-Zhen, Saijilafu, Teng, Zhao-Qian, Gao, Jun, Liu, Chang-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394843/
https://www.ncbi.nlm.nih.gov/pubmed/32775759
http://dx.doi.org/10.1016/j.ibror.2020.07.005