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Increase in blood–brain barrier leakage in healthy, older adults

Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which affects neuronal functioning. Currently, dynamic contrast-enhanced (DCE) MRI is the preferred in-vivo method to quantify BBB leakage. Dedicated DCE MRI studies in normal aging individuals are lacking, which coul...

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Detalles Bibliográficos
Autores principales: Verheggen, Inge C. M., de Jong, Joost J. A., van Boxtel, Martin P. J., Gronenschild, Ed H. B. M., Palm, Walter M., Postma, Alida A., Jansen, Jacobus F. A., Verhey, Frans R. J., Backes, Walter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394987/
https://www.ncbi.nlm.nih.gov/pubmed/32601792
http://dx.doi.org/10.1007/s11357-020-00211-2