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Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway

It is well known that excessive cholesterol accumulation within hepatocytes deteriorates nonalcoholic fatty liver disease (NAFLD). Augmenter of liver regeneration (ALR) has been reported to alleviate NAFLD through anti‐apoptosis; however, whether ALR could protect liver from cholesterol‐induced NAFL...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Dong, Ling‐yue, Gai, Qu‐jing, Ai, Wei‐lun, Wu, Yuan, Xiao, Wei‐chun, Zhang, Jing, An, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395071/
https://www.ncbi.nlm.nih.gov/pubmed/32766475
http://dx.doi.org/10.1002/hep4.1532