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Mapping allosteric communications within individual proteins

Allostery in proteins influences various biological processes such as regulation of gene transcription and activities of enzymes and cell signaling. Computational approaches for analysis of allosteric coupling provide inexpensive opportunities to predict mutations and to design small-molecule agents...

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Detalles Bibliográficos
Autores principales:	Wang, Jian, Jain, Abha, McDonald, Leanna R., Gambogi, Craig, Lee, Andrew L., Dokholyan, Nikolay V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395124/ https://www.ncbi.nlm.nih.gov/pubmed/32737291 http://dx.doi.org/10.1038/s41467-020-17618-2

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