Cargando…
Vitamin K-dependent carboxylation of coagulation factors: insights from a cell-based functional study
Vitamin K-dependent carboxylation is a post-translational modification essential for the biological function of coagulation factors. Defects in carboxylation are mainly associated with bleeding disorders. With the discovery of new vitamin K-dependent proteins, the importance of carboxylation now enc...
Autores principales: | Hao, Zhenyu, Jin, Da-Yun, Stafford, Darrel W., Tie, Jian-Ke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395276/ https://www.ncbi.nlm.nih.gov/pubmed/31624106 http://dx.doi.org/10.3324/haematol.2019.229047 |
Ejemplares similares
-
Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions
por: Sinhadri, Balaji Chandra Sekhar, et al.
Publicado: (2017) -
A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase
por: Jin, Da-Yun, et al.
Publicado: (2023) -
Extravascular FIX and coagulation
por: Stafford, Darrel W.
Publicado: (2016) -
Comparative sequence analysis of vitamin K‐dependent coagulation factors
por: Stojanovski, Bosko M., et al.
Publicado: (2022) -
Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family
por: Dahms, Sven O., et al.
Publicado: (2019)