EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase

Metabolic reprogramming of leukemia cells is important for survival, proliferation, and drug resistance under conditions of metabolic stress in the bone marrow. Deregulation of cellular metabolism, leading to development of leukemia, occurs through abnormally high expression of transcription factors...

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Detalles Bibliográficos
Autores principales: Saito, Yusuke, Sawa, Daisuke, Kinoshita, Mariko, Yamada, Ai, Kamimura, Sachiyo, Suekane, Akira, Ogoh, Honami, Matsuo, Hidemasa, Adachi, Souichi, Taga, Takashi, Tomizawa, Daisuke, Osato, Motomi, Soga, Tomoyoshi, Morishita, Kazuhiro, Moritake, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395283/
https://www.ncbi.nlm.nih.gov/pubmed/31649131
http://dx.doi.org/10.3324/haematol.2019.225953

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