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Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection
BACKGROUND AND AIMS: The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing. The identification of risk factors for severe outcomes is important. Dyslipidemia has been shown as a long-known risk factor for cardiovascular disease. The aim of this study is...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Diabetes India. Published by Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395301/ https://www.ncbi.nlm.nih.gov/pubmed/32771919 http://dx.doi.org/10.1016/j.dsx.2020.07.054 |
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author | Hariyanto, Timotius Ivan Kurniawan, Andree |
author_facet | Hariyanto, Timotius Ivan Kurniawan, Andree |
author_sort | Hariyanto, Timotius Ivan |
collection | PubMed |
description | BACKGROUND AND AIMS: The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing. The identification of risk factors for severe outcomes is important. Dyslipidemia has been shown as a long-known risk factor for cardiovascular disease. The aim of this study is to analyze the potential association between dyslipidemia and the severity of COVID-19 infection. METHODS: We systematically searched the PubMed database using specific keywords related to our aims until July 9th, 2020. All articles published on COVID-19 and dyslipidemia were retrieved. Statistical analysis was done using Review Manager 5.4 software. RESULTS: A total of 7 studies with a total of 6922 patients were included in our analysis. Our meta-analysis showed that dyslipidemia is associated with severe COVID-19 infections [RR 1.39 (95% CI 1.03–1.87), p = 0.03, I(2) = 57%, random-effect modelling]. CONCLUSION: Dyslipidemia increases the risk of the development of severe outcomes from COVID-19 infections. Patients with dyslipidemia should be monitored closely to minimize the risk of COVID-19. |
format | Online Article Text |
id | pubmed-7395301 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Diabetes India. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73953012020-08-03 Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection Hariyanto, Timotius Ivan Kurniawan, Andree Diabetes Metab Syndr Article BACKGROUND AND AIMS: The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing. The identification of risk factors for severe outcomes is important. Dyslipidemia has been shown as a long-known risk factor for cardiovascular disease. The aim of this study is to analyze the potential association between dyslipidemia and the severity of COVID-19 infection. METHODS: We systematically searched the PubMed database using specific keywords related to our aims until July 9th, 2020. All articles published on COVID-19 and dyslipidemia were retrieved. Statistical analysis was done using Review Manager 5.4 software. RESULTS: A total of 7 studies with a total of 6922 patients were included in our analysis. Our meta-analysis showed that dyslipidemia is associated with severe COVID-19 infections [RR 1.39 (95% CI 1.03–1.87), p = 0.03, I(2) = 57%, random-effect modelling]. CONCLUSION: Dyslipidemia increases the risk of the development of severe outcomes from COVID-19 infections. Patients with dyslipidemia should be monitored closely to minimize the risk of COVID-19. Diabetes India. Published by Elsevier Ltd. 2020 2020-08-01 /pmc/articles/PMC7395301/ /pubmed/32771919 http://dx.doi.org/10.1016/j.dsx.2020.07.054 Text en © 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hariyanto, Timotius Ivan Kurniawan, Andree Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title | Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title_full | Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title_fullStr | Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title_full_unstemmed | Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title_short | Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection |
title_sort | dyslipidemia is associated with severe coronavirus disease 2019 (covid-19) infection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395301/ https://www.ncbi.nlm.nih.gov/pubmed/32771919 http://dx.doi.org/10.1016/j.dsx.2020.07.054 |
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