Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure

BACKGROUND: To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure. CASE PRESENTATION: A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, w...

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Autores principales: Muns, Sofía M., González, Mónica P., Villegas, Victor M., de la Vega, Gabriela, Ventura, Camila V., Berrocal, Audina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395399/
https://www.ncbi.nlm.nih.gov/pubmed/32765899
http://dx.doi.org/10.1186/s40942-020-00240-1
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author Muns, Sofía M.
González, Mónica P.
Villegas, Victor M.
de la Vega, Gabriela
Ventura, Camila V.
Berrocal, Audina M.
author_facet Muns, Sofía M.
González, Mónica P.
Villegas, Victor M.
de la Vega, Gabriela
Ventura, Camila V.
Berrocal, Audina M.
author_sort Muns, Sofía M.
collection PubMed
description BACKGROUND: To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure. CASE PRESENTATION: A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis. CONCLUSIONS: This is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported.
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spelling pubmed-73953992020-08-05 Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure Muns, Sofía M. González, Mónica P. Villegas, Victor M. de la Vega, Gabriela Ventura, Camila V. Berrocal, Audina M. Int J Retina Vitreous Case Report BACKGROUND: To report a case of morning glory disc anomaly (MGDA) in a pediatric patient with prenatal Zika virus (ZIKV) exposure. CASE PRESENTATION: A 3-year-old male with prenatal exposure to ZIKV, confirmed by real-time polymerase chain reaction testing during the second trimester of pregnancy, was evaluated due to visual loss. Physical examination was remarkable for unilateral MGDA. Neuroimaging showed a base of skull encephalocele through the floor of the sella and callosal dysgenesis. CONCLUSIONS: This is the first report to suggest an association between prenatal ZIKV exposure and MGDA. Prenatal ZIKV exposure may be associated to a wider pathologic spectrum than previously reported. BioMed Central 2020-08-01 /pmc/articles/PMC7395399/ /pubmed/32765899 http://dx.doi.org/10.1186/s40942-020-00240-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Muns, Sofía M.
González, Mónica P.
Villegas, Victor M.
de la Vega, Gabriela
Ventura, Camila V.
Berrocal, Audina M.
Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title_full Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title_fullStr Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title_full_unstemmed Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title_short Unilateral morning glory disc anomaly in a patient with prenatal Zika virus exposure
title_sort unilateral morning glory disc anomaly in a patient with prenatal zika virus exposure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395399/
https://www.ncbi.nlm.nih.gov/pubmed/32765899
http://dx.doi.org/10.1186/s40942-020-00240-1
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