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Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report

BACKGROUND: Listeriosis is a severe food-borne infection caused by the Gram-positive rod, Listeria monocytogenes. Despite the low incidence (3–8 cases per million), Listeriosis has a case fatality rate of 20–30% as it occurs predominantly in immunocompromised individuals at extremes of age, diabetic...

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Autores principales: Al Ohaly, Rand, Ranganath, Nischal, Saffie, Medina G., Shroff, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395412/
https://www.ncbi.nlm.nih.gov/pubmed/32736610
http://dx.doi.org/10.1186/s12879-020-05286-y
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author Al Ohaly, Rand
Ranganath, Nischal
Saffie, Medina G.
Shroff, Anjali
author_facet Al Ohaly, Rand
Ranganath, Nischal
Saffie, Medina G.
Shroff, Anjali
author_sort Al Ohaly, Rand
collection PubMed
description BACKGROUND: Listeriosis is a severe food-borne infection caused by the Gram-positive rod, Listeria monocytogenes. Despite the low incidence (3–8 cases per million), Listeriosis has a case fatality rate of 20–30% as it occurs predominantly in immunocompromised individuals at extremes of age, diabetics and pregnant women. Listeriosis classically presents as a febrile gastroenteritis, isolated bacteremia, meningitis, or maternal-fetal infections. Focal bone and joint infection are rare and primarily involve orthopedic implant devices. Here, we present the first case of Listeria-associated spondylodiscitis. CASE PRESENTATION: A 79-year-old male presents with acute-on-chronic back pain in the absence of risk factors or exposures, aside from age. On radiological imaging, spondylodiscitis of L3-L4 was diagnosed. Subsequently, a CT-guided biopsy was performed to aid in confirming microbiological aetiology. Listeria monocytogenes was grown in culture and patient received appropriate antibacterial therapy. CONCLUSION: The case highlights the utility of image-guided tissue sampling in aiding diagnosis and management in patients with vertebral osteomyelitis. It also encourages consideration of uncommon organisms such as Listeria as an etiology of vertebral osteomyelitis, even in the absence of prosthetic implants.
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spelling pubmed-73954122020-08-05 Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report Al Ohaly, Rand Ranganath, Nischal Saffie, Medina G. Shroff, Anjali BMC Infect Dis Case Report BACKGROUND: Listeriosis is a severe food-borne infection caused by the Gram-positive rod, Listeria monocytogenes. Despite the low incidence (3–8 cases per million), Listeriosis has a case fatality rate of 20–30% as it occurs predominantly in immunocompromised individuals at extremes of age, diabetics and pregnant women. Listeriosis classically presents as a febrile gastroenteritis, isolated bacteremia, meningitis, or maternal-fetal infections. Focal bone and joint infection are rare and primarily involve orthopedic implant devices. Here, we present the first case of Listeria-associated spondylodiscitis. CASE PRESENTATION: A 79-year-old male presents with acute-on-chronic back pain in the absence of risk factors or exposures, aside from age. On radiological imaging, spondylodiscitis of L3-L4 was diagnosed. Subsequently, a CT-guided biopsy was performed to aid in confirming microbiological aetiology. Listeria monocytogenes was grown in culture and patient received appropriate antibacterial therapy. CONCLUSION: The case highlights the utility of image-guided tissue sampling in aiding diagnosis and management in patients with vertebral osteomyelitis. It also encourages consideration of uncommon organisms such as Listeria as an etiology of vertebral osteomyelitis, even in the absence of prosthetic implants. BioMed Central 2020-07-31 /pmc/articles/PMC7395412/ /pubmed/32736610 http://dx.doi.org/10.1186/s12879-020-05286-y Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Al Ohaly, Rand
Ranganath, Nischal
Saffie, Medina G.
Shroff, Anjali
Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title_full Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title_fullStr Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title_full_unstemmed Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title_short Listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
title_sort listeria spondylodiscitis: an uncommon etiology of a common condition; a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395412/
https://www.ncbi.nlm.nih.gov/pubmed/32736610
http://dx.doi.org/10.1186/s12879-020-05286-y
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