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Biochanin-A ameliorates pulmonary fibrosis by suppressing the TGF-β mediated EMT, myofibroblasts differentiation and collagen deposition in in vitro and in vivo systems

Background: Idiopathic Pulmonary Fibrosis (IPF) is a progressive inflammatory disorder driven by a fibrotic cascade of events such as epithelial to mesenchymal transition, extracellular matrix production and collagen formation in the lungs in a sequential manner. IPF incidences were raising rapidly...

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Detalles Bibliográficos
Autores principales: Andugulapati, Sai Balaji, Gourishetti, Karthik, Tirunavalli, Satya Krishna, Shaikh, Taslim Babru, Sistla, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395646/
https://www.ncbi.nlm.nih.gov/pubmed/32781391
http://dx.doi.org/10.1016/j.phymed.2020.153298