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Preemptive Nalbuphine Attenuates Remifentanil-Induced Postoperative Hyperalgesia After Laparoscopic Cholecystectomy: A Prospective Randomized Double-Blind Clinical Trial

BACKGROUND: Remifentanil-induced hyperalgesia (RIH) is a paradoxical phenomenon that may increase sensitivity to painful stimuli. Nalbuphine, which is both a μ-receptor antagonist and κ-receptor agonist, may affect RIH. The aim of this study was to evaluate the effects of nalbuphine on RIH during la...

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Detalles Bibliográficos
Autores principales:	Hu, Jun, Chen, Shuangshuang, Zhu, Mudan, Wu, Yun, Wang, Ping, Chen, Jinbao, Zhang, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395683/ https://www.ncbi.nlm.nih.gov/pubmed/32801849 http://dx.doi.org/10.2147/JPR.S257018

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