Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80

Chromatin regulates spatiotemporal gene expression during neurodevelopment, but it also mediates DNA damage repair essential to proliferating neural progenitor cells (NPCs). Here, we uncover molecularly dissociable roles for nucleosome remodeler Ino80 in chromatin-mediated transcriptional regulation...

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Detalles Bibliográficos
Autores principales: Keil, Jason M., Doyle, Daniel Z., Qalieh, Adel, Lam, Mandy M., Funk, Owen H., Qalieh, Yaman, Shi, Lei, Mohan, Nitesh, Sorel, Alice, Kwan, Kenneth Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395731/
https://www.ncbi.nlm.nih.gov/pubmed/32737294
http://dx.doi.org/10.1038/s41467-020-17551-4

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