Cargando…
Challenging infections in pregnancy
Maternal sepsis is “a life-threatening condition defined as organ dysfunction resulting from infection during pregnancy, childbirth, post-abortion, or postpartum period.” (World Health Organisation, 2017). Serious infection during, or immediately after, pregnancy may go initially unrecognized in an...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395812/ https://www.ncbi.nlm.nih.gov/pubmed/32837533 http://dx.doi.org/10.1016/j.ogrm.2020.06.005 |
_version_ | 1783565472383369216 |
---|---|
author | Morgan, Marina |
author_facet | Morgan, Marina |
author_sort | Morgan, Marina |
collection | PubMed |
description | Maternal sepsis is “a life-threatening condition defined as organ dysfunction resulting from infection during pregnancy, childbirth, post-abortion, or postpartum period.” (World Health Organisation, 2017). Serious infection during, or immediately after, pregnancy may go initially unrecognized in an otherwise young and healthy group, who nevertheless do have a compromized immune system. Secondly, whilst malaise, flushes, nausea, vomiting and abdominal pain are common in pregnancy, each can herald sepsis with rapid demise for mother and baby. The MBRRACE-UK report in 2017(1) found an overall sepsis-related maternal mortality rate of 0.56 per 100,000 maternities with a mortality rate from genital tract sepsis of 0.28 per 100,000 maternities. This review will focus on the major causes, recognition, differentiation and microbiological management of sepsis in pregnancy, using two detailed cases to illustrate. |
format | Online Article Text |
id | pubmed-7395812 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73958122020-08-03 Challenging infections in pregnancy Morgan, Marina Obstet Gynaecol Reprod Med Case-Based Learning Maternal sepsis is “a life-threatening condition defined as organ dysfunction resulting from infection during pregnancy, childbirth, post-abortion, or postpartum period.” (World Health Organisation, 2017). Serious infection during, or immediately after, pregnancy may go initially unrecognized in an otherwise young and healthy group, who nevertheless do have a compromized immune system. Secondly, whilst malaise, flushes, nausea, vomiting and abdominal pain are common in pregnancy, each can herald sepsis with rapid demise for mother and baby. The MBRRACE-UK report in 2017(1) found an overall sepsis-related maternal mortality rate of 0.56 per 100,000 maternities with a mortality rate from genital tract sepsis of 0.28 per 100,000 maternities. This review will focus on the major causes, recognition, differentiation and microbiological management of sepsis in pregnancy, using two detailed cases to illustrate. Published by Elsevier Ltd. 2020-09 2020-08-01 /pmc/articles/PMC7395812/ /pubmed/32837533 http://dx.doi.org/10.1016/j.ogrm.2020.06.005 Text en Crown Copyright © 2020 Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case-Based Learning Morgan, Marina Challenging infections in pregnancy |
title | Challenging infections in pregnancy |
title_full | Challenging infections in pregnancy |
title_fullStr | Challenging infections in pregnancy |
title_full_unstemmed | Challenging infections in pregnancy |
title_short | Challenging infections in pregnancy |
title_sort | challenging infections in pregnancy |
topic | Case-Based Learning |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395812/ https://www.ncbi.nlm.nih.gov/pubmed/32837533 http://dx.doi.org/10.1016/j.ogrm.2020.06.005 |
work_keys_str_mv | AT morganmarina challenginginfectionsinpregnancy |