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Pharmacokinetics, tissue distribution and excretion of 6-O-demethylmenisporphine, a bioactive oxoisoaporphine alkaloid from Menispermi Rhizoma, as determined by a HPLC-MS/MS method

6-O-demethylmenisporphine, a major active oxoisoaporphine alkaloid isolated from Menispermi Rhizoma, has been confirmed to possess significant bioactivities, including anti-cancer and anti-hypoxia effects. However, few researches on quantifying 6-O-demethylmenisporphine in biosamples have been perfo...

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Detalles Bibliográficos
Autores principales:	Wei, Jinxia, Yu, Yingying, Li, Yanan, Shao, Jia, Li, Jianyu, Li, Lingzhi, Li, Yubo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395816/ https://www.ncbi.nlm.nih.gov/pubmed/32829132 http://dx.doi.org/10.1016/j.jchromb.2020.122297

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