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Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds
SARS-CoV-2 3C-like protease is the main protease of SARS-CoV-2 and has been considered as one of the key targets for drug discovery against COVID-19. We identified several N-substituted isatin compounds as potent SARS-CoV-2 3C-like protease inhibitors. The three most potent compounds inhibit SARS-Co...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Masson SAS.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395831/ https://www.ncbi.nlm.nih.gov/pubmed/32798789 http://dx.doi.org/10.1016/j.ejmech.2020.112702 |