Cargando…

Downregulation of CyclophilinA/CD147 Axis Induces Cell Apoptosis and Inhibits Glioma Aggressiveness

Gliomas are the most common primary tumors in the brain with poor prognosis. Previous studies have detected high expression of Cyclophilin A (CyPA) and CD147, respectively, in glioma. However, the correlation between their expressions and glioma prognosis remains unclear. Here, we investigated the e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Shengchao, Hu, Chi, Xiao, Zhiqiang, Luo, Chengke, Liu, Zhixiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396009/ https://www.ncbi.nlm.nih.gov/pubmed/32775435 http://dx.doi.org/10.1155/2020/7035847

Ejemplares similares

Dealing with the family: CD147 interactions with cyclophilins
por: Yurchenko, Vyacheslav, et al.
Publicado: (2006)

Shikonin inhibits proliferation and induces apoptosis in glioma cells via downregulation of CD147
por: Guo, Na, et al.
Publicado: (2019)

The Roles of CD147 and/or Cyclophilin A in Kidney Diseases
por: Qu, Xin, et al.
Publicado: (2014)

The level of CD147 expression correlates with cyclophilin-induced signalling and chemotaxis
por: Trachtenberg, Alexander, et al.
Publicado: (2011)

Cyclophilin–CD147 interactions: a new target for anti-inflammatory therapeutics
por: Yurchenko, V, et al.
Publicado: (2010)

Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19
por: Liu, Chenglong, et al.
Publicado: (2020)

Cyclophilin A/CD147 Interaction: A Promising Target for Anticancer Therapy
por: Han, Jang Mi, et al.
Publicado: (2022)

Hypoxia-Related lncRNA Correlates With Prognosis and Immune Microenvironment in Lower-Grade Glioma
por: Xu, Shengchao, et al.
Publicado: (2021)

A novel gene signature predicts chemoradiotherapy efficacy and tumor immunity in high‐grade glioma
por: Xu, Shengchao, et al.
Publicado: (2020)

Expression of m6A Regulators Correlated With Immune Microenvironment Predicts Therapeutic Efficacy and Prognosis in Gliomas
por: Xu, Shengchao, et al.
Publicado: (2020)

Immune-related genes with APA in microenvironment indicate risk stratification and clinical prognosis in grade II/III gliomas
por: Xu, Shengchao, et al.
Publicado: (2021)

CD147-Cyclophilin a Interactions Promote Proliferation and Survival of Cutaneous T-Cell Lymphoma
por: Sakamoto, Minami, et al.
Publicado: (2021)

Surgery combined with local 5-aminolevulinic acid-photodynamic therapy on skin cancer and its effect on the expression of cyclophilin A, cyclophilin B and CD147
por: Guo, Ling, et al.
Publicado: (2017)

Solution Characterization of the Extracellular Region of CD147 and Its Interaction with Its Enzyme Ligand Cyclophilin A
por: Schlegel, Jennifer, et al.
Publicado: (2009)

Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression
por: Zhao, Shuang, et al.
Publicado: (2018)

The Cyclophilin A-CD147 complex promotes bone marrow colonization of B-cell malignancies: implications for therapy
por: Zhu, Di, et al.
Publicado: (2015)

CD147 and cyclophilin A: a promising potential targeted therapy for COVID-19 and associated cancer progression and chemo-resistance
por: Bakhtiyari, Maryam, et al.
Publicado: (2023)

CD74 Correlated With Malignancies and Immune Microenvironment in Gliomas
por: Xu, Shengchao, et al.
Publicado: (2021)

Cyclophilin A Inhibitors Suppress Proliferation and Induce Apoptosis of MKN45 Gastric Cancer Stem-like Cells by Regulating CypA/CD147-Mediated Signaling Pathway
por: Cho, Hee Jeong, et al.
Publicado: (2023)

Downregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer
por: LUO, ZHIGUO, et al.
Publicado: (2014)

Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells
por: Kim, Ju-Young, et al.
Publicado: (2010)

Cyclophilin A secreted from fibroblast-like synoviocytes is involved in the induction of CD147 expression in macrophages of mice with collagen-induced arthritis
por: Nishioku, Tsuyoshi, et al.
Publicado: (2012)

Melittin inhibits the invasion of MCF-7 cells by downregulating CD147 and MMP-9 expression
por: Wang, Jianjun, et al.
Publicado: (2017)

Mycoplasma genitalium Protein of Adhesion Induces Inflammatory Cytokines via Cyclophilin A-CD147 Activating the ERK-NF-κB Pathway in Human Urothelial Cells
por: Li, Lingling, et al.
Publicado: (2020)

Whole transcriptome and proteome analyses identify potential targets and mechanisms underlying tumor treating fields against glioblastoma
por: Xu, Shengchao, et al.
Publicado: (2022)

Correction: Whole transcriptome and proteome analyses identify potential targets and mechanisms underlying tumor treating fields against glioblastoma
por: Xu, Shengchao, et al.
Publicado: (2022)

circMMD reduction following tumor treating fields inhibits glioblastoma progression through FUBP1/FIR/DVL1 and miR-15b-5p/FZD6 signaling
por: Xu, Shengchao, et al.
Publicado: (2023)

CTLA-4 correlates with immune and clinical characteristics of glioma
por: Liu, Fangkun, et al.
Publicado: (2020)

Autophagy induced by baicalin involves downregulation of CD147 in SMMC-7721 cells in vitro
por: ZHANG, XIANJIAO, et al.
Publicado: (2011)

Cyclophilin A/CD147 signaling induces the epithelial-to-mesenchymal transition and renal fibrosis in chronic allograft dysfunction by regulating p38 MAPK signaling
por: Liu, Xuzhong, et al.
Publicado: (2022)

SP-8356, a Novel Inhibitor of CD147-Cyclophilin A Interactions, Reduces Plaque Progression and Stabilizes Vulnerable Plaques in apoE-Deficient Mice
por: Pahk, Kisoo, et al.
Publicado: (2019)

A Nanoparticle-Conjugated Anti-TBK1 siRNA Induces Autophagy-Related Apoptosis and Enhances cGAS-STING Pathway in GBM Cells
por: Xu, Shengchao, et al.
Publicado: (2021)

Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals
por: Fukuchi, Keisuke, et al.
Publicado: (2022)

Cyclophilin A contributes to shikonin-induced glioma cell necroptosis and promotion of chromatinolysis
por: Wang, Xinyu, et al.
Publicado: (2022)

CD147 expression was positively linked to aggressiveness and worse prognosis of gastric cancer: a meta and bioinformatics analysis
por: Zheng, Hua-Chuan, et al.
Publicado: (2017)

Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells
por: Qian, Ai-Rong, et al.
Publicado: (2008)

Natural Cyclophilin A Inhibitors Suppress the Growth of Cancer Stem Cells in Non-Small Cell Lung Cancer by Disrupting Crosstalk between CypA/CD147 and EGFR
por: Han, Jang Mi, et al.
Publicado: (2023)

Cyclophilins and cyclophilin inhibitors in nidovirus replication
por: de Wilde, Adriaan H., et al.
Publicado: (2018)

Galangin inhibits epithelial-mesenchymal transition and angiogenesis by downregulating CD44 in glioma
por: Chen, Daliang, et al.
Publicado: (2019)

Scutellarin inhibits the glioma cell proliferation by downregulating BIRC5 to promote cell apoptosis
por: Wang, Feng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_psle9do7srcbulqlr1ki7lqr9s