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The Role of Gastric Mucosal Immunity in Gastric Diseases

Gastric mucosa plays its immune function through innate and adaptive immunity by recruiting immune cells and releasing corresponding cytokines, which have an inseparable relationship with gastric diseases. Whether infective gastric diseases caused by Helicobacter pylori, Epstein-Barr virus or other...

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Detalles Bibliográficos
Autores principales: Nie, Siru, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396052/
https://www.ncbi.nlm.nih.gov/pubmed/32775468
http://dx.doi.org/10.1155/2020/7927054
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author Nie, Siru
Yuan, Yuan
author_facet Nie, Siru
Yuan, Yuan
author_sort Nie, Siru
collection PubMed
description Gastric mucosa plays its immune function through innate and adaptive immunity by recruiting immune cells and releasing corresponding cytokines, which have an inseparable relationship with gastric diseases. Whether infective gastric diseases caused by Helicobacter pylori, Epstein-Barr virus or other microbe, noninfective gastric diseases, or gastric cancer, gastric mucosal immunity plays an important role in the occurrence and development of the disease. Understanding the unique immune-related tissue structure of the gastric mucosa and its role in immune responses can help prevent gastric diseases or treat them through immunotherapy. In this review, we summarize the basic feature of gastric mucosal immunity and its relationship with gastric diseases to track the latest progress of gastric mucosal immunity, update relevant knowledge and provide theoretical reference for the prevention and treatment of gastric diseases based on the gastric mucosal immunity.
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spelling pubmed-73960522020-08-07 The Role of Gastric Mucosal Immunity in Gastric Diseases Nie, Siru Yuan, Yuan J Immunol Res Review Article Gastric mucosa plays its immune function through innate and adaptive immunity by recruiting immune cells and releasing corresponding cytokines, which have an inseparable relationship with gastric diseases. Whether infective gastric diseases caused by Helicobacter pylori, Epstein-Barr virus or other microbe, noninfective gastric diseases, or gastric cancer, gastric mucosal immunity plays an important role in the occurrence and development of the disease. Understanding the unique immune-related tissue structure of the gastric mucosa and its role in immune responses can help prevent gastric diseases or treat them through immunotherapy. In this review, we summarize the basic feature of gastric mucosal immunity and its relationship with gastric diseases to track the latest progress of gastric mucosal immunity, update relevant knowledge and provide theoretical reference for the prevention and treatment of gastric diseases based on the gastric mucosal immunity. Hindawi 2020-07-24 /pmc/articles/PMC7396052/ /pubmed/32775468 http://dx.doi.org/10.1155/2020/7927054 Text en Copyright © 2020 Siru Nie and Yuan Yuan. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Nie, Siru
Yuan, Yuan
The Role of Gastric Mucosal Immunity in Gastric Diseases
title The Role of Gastric Mucosal Immunity in Gastric Diseases
title_full The Role of Gastric Mucosal Immunity in Gastric Diseases
title_fullStr The Role of Gastric Mucosal Immunity in Gastric Diseases
title_full_unstemmed The Role of Gastric Mucosal Immunity in Gastric Diseases
title_short The Role of Gastric Mucosal Immunity in Gastric Diseases
title_sort role of gastric mucosal immunity in gastric diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396052/
https://www.ncbi.nlm.nih.gov/pubmed/32775468
http://dx.doi.org/10.1155/2020/7927054
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