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Bradykinin 1 Receptor Antagonist BI1026706 Does Not Reduce Central Retinal Thickness in Center-Involved Diabetic Macular Edema

PURPOSE: The bradykinin 1 receptor may be important in inflammatory retinal vascular leakage in diabetic macular edema. BI 1026706 is an antagonist of bradykinin 1 receptor that has demonstrated efficacy in preclinical studies. Boehringer Ingelheim trial 1320.22 (NCT02732951) was a randomized, doubl...

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Detalles Bibliográficos
Autores principales:	Lang, Gabriele E., Tadayoni, Ramin, Tang, Wenbo, Barth, Claudia, Weiss-Haljiti, Cornelia, Chong, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Clinical Trials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396196/ https://www.ncbi.nlm.nih.gov/pubmed/32818112 http://dx.doi.org/10.1167/tvst.9.4.25

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