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Integrated analysis of miRNAs and DNA methylation identifies miR‐132‐3p as a tumor suppressor in lung adenocarcinoma

BACKGROUND: Aberrant miRNA expression and DNA methylation are two major epigenetic events in lung adenocarcinoma (LUAD). We conducted a combined analysis of the molecular changes in LUAD. METHODS: We analyzed differentially expressed miRNAs and methylated CpG loci in 489 LUAD tissues versus 49 norma...

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Detalles Bibliográficos
Autores principales: Su, Yun, Shetty, Amol, Jiang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396385/
https://www.ncbi.nlm.nih.gov/pubmed/32500672
http://dx.doi.org/10.1111/1759-7714.13497