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Maackiain, a compound derived from Sophora flavescens, increases IL‐1β production by amplifying nigericin‐mediated inflammasome activation

Sophora flavescens is used as a traditional herbal medicine to modulate inflammatory responses. However, little is known about the impact of (‐)‐maackiain, a compound derived from S. flavescens, on the activation of inflammasome/caspase‐1, a key factor in interleukin‐1β (IL‐1β) processing. Here, we...

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Detalles Bibliográficos
Autores principales: Huh, Jin‐Won, Lee, Jung‐Hoon, Jeon, Eekhyoung, Ryu, Hyung Won, Oh, Sei‐Ryang, Ahn, Kyung‐Seop, Jun, Hyun Sik, Ha, Un‐Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396426/
https://www.ncbi.nlm.nih.gov/pubmed/32428336
http://dx.doi.org/10.1002/2211-5463.12899

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