A mouse model of Timothy syndrome exhibits altered social competitive dominance and inhibitory neuron development

Multiple genetic factors related to autism spectrum disorder (ASD) have been identified, but the biological mechanisms remain obscure. Timothy syndrome (TS), associated with syndromic ASD, is caused by a gain‐of‐function mutation, G406R, in the pore‐forming subunit of L‐type Ca(2+) channels, Ca(v)1....

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Detalles Bibliográficos
Autores principales: Horigane, Shin‐ichiro, Ozawa, Yukihiro, Zhang, Jun, Todoroki, Hiroe, Miao, Pan, Haijima, Asahi, Yanagawa, Yuchio, Ueda, Shuhei, Nakamura, Shigeo, Kakeyama, Masaki, Takemoto‐Kimura, Sayaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396430/
https://www.ncbi.nlm.nih.gov/pubmed/32598571
http://dx.doi.org/10.1002/2211-5463.12924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396430/
https://www.ncbi.nlm.nih.gov/pubmed/32598571
http://dx.doi.org/10.1002/2211-5463.12924

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