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Puromycin aminonucleoside‐induced podocyte injury is ameliorated by the Smad3 inhibitor SIS3

Smad3 signaling and transgelin expression are often activated during puromycin aminonucleoside (PAN)‐induced podocyte injury. Here, we investigated whether the Smad3 inhibitor SIS3 can ameliorate damage to injured podocytes. A model of PAN‐induced podocyte injury was constructed using the MPC5 cell...

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Detalles Bibliográficos
Autores principales: Jiang, Lina, Cui, Hong, Ding, Jie, Yang, Aijun, Zhang, Yingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396432/
https://www.ncbi.nlm.nih.gov/pubmed/32583562
http://dx.doi.org/10.1002/2211-5463.12916