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Phase Transition of Huntingtin: Factors and Pathological Relevance

Formation of intracellular mutant Huntingtin (mHtt) aggregates is a hallmark of Huntington’s disease (HD). The mechanisms underlying mHtt aggregation, however, are still not fully understood. A few recent studies indicated mHtt undergoes phase transition, bringing new clues to understand how mHtt ag...

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Detalles Bibliográficos
Autores principales:	Yang, Junsheng, Yang, Xiaotong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396480/ https://www.ncbi.nlm.nih.gov/pubmed/32849783 http://dx.doi.org/10.3389/fgene.2020.00754

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