CD226: An Emerging Role in Immunologic Diseases

CD226, a member of the immunoglobulin superfamily, is a functional protein initially expressed on natural killer and T cells. In recent years, the function of CD226 has been increasingly realized and researched. Accumulating evidence shows that CD226 is closely related to the occurrence of autoimmun...

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Autores principales: Huang, Zhiyi, Qi, Guangyin, Miller, Joseph S., Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396508/
https://www.ncbi.nlm.nih.gov/pubmed/32850777
http://dx.doi.org/10.3389/fcell.2020.00564
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author Huang, Zhiyi
Qi, Guangyin
Miller, Joseph S.
Zheng, Song Guo
author_facet Huang, Zhiyi
Qi, Guangyin
Miller, Joseph S.
Zheng, Song Guo
author_sort Huang, Zhiyi
collection PubMed
description CD226, a member of the immunoglobulin superfamily, is a functional protein initially expressed on natural killer and T cells. In recent years, the function of CD226 has been increasingly realized and researched. Accumulating evidence shows that CD226 is closely related to the occurrence of autoimmune diseases, infectious diseases, and tumors. Because of the CD226’s increasing importance, the author herein discusses the structure, mechanism of action, and role of CD226 in various pathophysiological environments, allowing for further understanding of the function of CD226 and providing the basis for further research in related diseases.
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spelling pubmed-73965082020-08-25 CD226: An Emerging Role in Immunologic Diseases Huang, Zhiyi Qi, Guangyin Miller, Joseph S. Zheng, Song Guo Front Cell Dev Biol Cell and Developmental Biology CD226, a member of the immunoglobulin superfamily, is a functional protein initially expressed on natural killer and T cells. In recent years, the function of CD226 has been increasingly realized and researched. Accumulating evidence shows that CD226 is closely related to the occurrence of autoimmune diseases, infectious diseases, and tumors. Because of the CD226’s increasing importance, the author herein discusses the structure, mechanism of action, and role of CD226 in various pathophysiological environments, allowing for further understanding of the function of CD226 and providing the basis for further research in related diseases. Frontiers Media S.A. 2020-07-24 /pmc/articles/PMC7396508/ /pubmed/32850777 http://dx.doi.org/10.3389/fcell.2020.00564 Text en Copyright © 2020 Huang, Qi, Miller and Zheng. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Huang, Zhiyi
Qi, Guangyin
Miller, Joseph S.
Zheng, Song Guo
CD226: An Emerging Role in Immunologic Diseases
title CD226: An Emerging Role in Immunologic Diseases
title_full CD226: An Emerging Role in Immunologic Diseases
title_fullStr CD226: An Emerging Role in Immunologic Diseases
title_full_unstemmed CD226: An Emerging Role in Immunologic Diseases
title_short CD226: An Emerging Role in Immunologic Diseases
title_sort cd226: an emerging role in immunologic diseases
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396508/
https://www.ncbi.nlm.nih.gov/pubmed/32850777
http://dx.doi.org/10.3389/fcell.2020.00564
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AT zhengsongguo cd226anemergingroleinimmunologicdiseases

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