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Evaluation of Long-Time Decoction-Detoxicated Hei-Shun-Pian (Processed Aconitum carmichaeli Debeaux Lateral Root With Peel) for Its Acute Toxicity and Therapeutic Effect on Mono-Iodoacetate Induced Osteoarthritis
BACKGROUND: As a degenerative joint disease with severe cartilage destruction and pain, osteoarthritis (OA) has no satisfactory therapy to date. In traditional Chinese medicine (TCM), Aconitum carmichaeli Debeaux derived Hei-shun-pian (Hsp) has been developed for joint pain treatment. However, it ca...
Autores principales: | Zhang, Lei, Li, Ting, Wang, Rongrong, Xu, Jiaan, Zhou, Li, Yan, Li, Hu, Zhengyan, Li, Hongwen, Liu, Fucun, Du, Wenxi, Tong, Peijian, Wu, Huiling, Zhang, Shanxing, Shan, Letian, Efferth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396609/ https://www.ncbi.nlm.nih.gov/pubmed/32848727 http://dx.doi.org/10.3389/fphar.2020.01053 |
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