Cargando…
DDHD1, but Not DDHD2, Suppresses Neurite Outgrowth in SH-SY5Y and PC12 Cells by Regulating Protein Transport From Recycling Endosomes
DDHD1 and DDHD2 are both intracellular phospholipases A(1) and hydrolyze phosphatidic acid in vitro. Given that phosphatidic acid participates in neurite outgrowth, we examined whether DDHD1 and DDHD2 regulate neurite outgrowth. Depletion of DDHD1 from SH-SY5Y and PC12 cells caused elongation of neu...
Autores principales: | Maemoto, Yuki, Maruyama, Tomohiro, Nemoto, Kazuaki, Baba, Takashi, Motohashi, Manae, Ito, Akihiro, Tagaya, Mitsuo, Tani, Katsuko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396612/ https://www.ncbi.nlm.nih.gov/pubmed/32850804 http://dx.doi.org/10.3389/fcell.2020.00670 |
Ejemplares similares
-
Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis
por: Maruyama, Tomohiro, et al.
Publicado: (2018) -
Late-onset spastic ataxia phenotype in a patient with a homozygous DDHD2 mutation
por: Doi, Hiroshi, et al.
Publicado: (2014) -
The phospholipase DDHD1 as a new target in colorectal cancer therapy
por: Raimondo, Stefania, et al.
Publicado: (2018) -
Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization
por: Matsumoto, Naoki, et al.
Publicado: (2021) -
Biallelic
DDHD2
mutations in patients with adult‐onset complex hereditary spastic paraplegia
por: Chou, Ying‐Tsen, et al.
Publicado: (2023)