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DDHD1, but Not DDHD2, Suppresses Neurite Outgrowth in SH-SY5Y and PC12 Cells by Regulating Protein Transport From Recycling Endosomes

DDHD1 and DDHD2 are both intracellular phospholipases A(1) and hydrolyze phosphatidic acid in vitro. Given that phosphatidic acid participates in neurite outgrowth, we examined whether DDHD1 and DDHD2 regulate neurite outgrowth. Depletion of DDHD1 from SH-SY5Y and PC12 cells caused elongation of neu...

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Detalles Bibliográficos
Autores principales: Maemoto, Yuki, Maruyama, Tomohiro, Nemoto, Kazuaki, Baba, Takashi, Motohashi, Manae, Ito, Akihiro, Tagaya, Mitsuo, Tani, Katsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396612/
https://www.ncbi.nlm.nih.gov/pubmed/32850804
http://dx.doi.org/10.3389/fcell.2020.00670

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