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Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment
BACKGROUND: Late-life depression is a major public health concern, driving the development of complementary treatment options. This study investigates the effectiveness and acceptability of internet-based Cognitive Behavioral Therapy (iCBT) in older individuals (60+ years) compared to younger age gr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396625/ https://www.ncbi.nlm.nih.gov/pubmed/32848915 http://dx.doi.org/10.3389/fpsyt.2020.00735 |
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author | Pabst, Alexander Löbner, Margrit Stein, Janine Luppa, Melanie Kersting, Anette König, Hans-Helmut Riedel-Heller, Steffi G. |
author_facet | Pabst, Alexander Löbner, Margrit Stein, Janine Luppa, Melanie Kersting, Anette König, Hans-Helmut Riedel-Heller, Steffi G. |
author_sort | Pabst, Alexander |
collection | PubMed |
description | BACKGROUND: Late-life depression is a major public health concern, driving the development of complementary treatment options. This study investigates the effectiveness and acceptability of internet-based Cognitive Behavioral Therapy (iCBT) in older individuals (60+ years) compared to younger age groups. MATERIALS AND METHODS: Secondary analysis of a cluster-randomized controlled trial with 647 (18–82 years; mean 43.9) mild to moderately severe depressed primary care patients receiving either iCBT + treatment as usual (TAU) or TAU alone. Severity of depression was measured by the Beck Depression Inventory (BDI-II) at baseline, 6 weeks and 6 months. Intention-to-treat analysis in three age groups (18–39 years, n = 264; 40–59 years, n = 300; 60+ years, n = 83) was performed, using mixed-effects regression models to quantify treatment effect. RESULTS: No age differences in the effectiveness of iCBT were found. Patients in the intervention group consistently showed a greater reduction in depression severity than controls in all three age groups and at both follow-ups. Effect sizes ranged from d = 0.30 (40–59 years, 6 weeks) to d = 1.91 (60+ years, 6 months). Uptake of the intervention was banded around 70% with no differences between age groups (χ² = 0.18, p = .915). The mean number of completed modules increased with age (χ² = 18.99, p = .040). DISCUSSION: iCBT is equally effective in both younger and older individuals, thus providing a valuable complementary element of routine late-life depression care. CLINICAL TRIAL REGISTRATION: DRKS-ID: DRKS00005075 https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00005075 |
format | Online Article Text |
id | pubmed-7396625 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73966252020-08-25 Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment Pabst, Alexander Löbner, Margrit Stein, Janine Luppa, Melanie Kersting, Anette König, Hans-Helmut Riedel-Heller, Steffi G. Front Psychiatry Psychiatry BACKGROUND: Late-life depression is a major public health concern, driving the development of complementary treatment options. This study investigates the effectiveness and acceptability of internet-based Cognitive Behavioral Therapy (iCBT) in older individuals (60+ years) compared to younger age groups. MATERIALS AND METHODS: Secondary analysis of a cluster-randomized controlled trial with 647 (18–82 years; mean 43.9) mild to moderately severe depressed primary care patients receiving either iCBT + treatment as usual (TAU) or TAU alone. Severity of depression was measured by the Beck Depression Inventory (BDI-II) at baseline, 6 weeks and 6 months. Intention-to-treat analysis in three age groups (18–39 years, n = 264; 40–59 years, n = 300; 60+ years, n = 83) was performed, using mixed-effects regression models to quantify treatment effect. RESULTS: No age differences in the effectiveness of iCBT were found. Patients in the intervention group consistently showed a greater reduction in depression severity than controls in all three age groups and at both follow-ups. Effect sizes ranged from d = 0.30 (40–59 years, 6 weeks) to d = 1.91 (60+ years, 6 months). Uptake of the intervention was banded around 70% with no differences between age groups (χ² = 0.18, p = .915). The mean number of completed modules increased with age (χ² = 18.99, p = .040). DISCUSSION: iCBT is equally effective in both younger and older individuals, thus providing a valuable complementary element of routine late-life depression care. CLINICAL TRIAL REGISTRATION: DRKS-ID: DRKS00005075 https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00005075 Frontiers Media S.A. 2020-07-24 /pmc/articles/PMC7396625/ /pubmed/32848915 http://dx.doi.org/10.3389/fpsyt.2020.00735 Text en Copyright © 2020 Pabst, Löbner, Stein, Luppa, Kersting, König and Riedel-Heller http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychiatry Pabst, Alexander Löbner, Margrit Stein, Janine Luppa, Melanie Kersting, Anette König, Hans-Helmut Riedel-Heller, Steffi G. Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title | Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title_full | Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title_fullStr | Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title_full_unstemmed | Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title_short | Internet-Based Cognitive Behavior Therapy Only for the Young? A Secondary Analysis of a Randomized Controlled Trial of Depression Treatment |
title_sort | internet-based cognitive behavior therapy only for the young? a secondary analysis of a randomized controlled trial of depression treatment |
topic | Psychiatry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396625/ https://www.ncbi.nlm.nih.gov/pubmed/32848915 http://dx.doi.org/10.3389/fpsyt.2020.00735 |
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