Histone H2A-Reactive B Cells Are Functionally Anergic in Healthy Mice With Potential to Provide Humoral Protection Against HIV-1

Peripheral tolerance is essential for silencing weakly autoreactive B cells that have escaped central tolerance, but it is unclear why these potentially pathogenic B cells are retained rather than being eliminated entirely. Release from peripheral tolerance restraint can occur under certain circumst...

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Detalles Bibliográficos
Autores principales: Agazio, Amanda, Cimons, Jennifer, Shotts, Kristin M., Guo, Kejun, Santiago, Mario L., Pelanda, Roberta, Torres, Raul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396680/
https://www.ncbi.nlm.nih.gov/pubmed/32849530
http://dx.doi.org/10.3389/fimmu.2020.01565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396680/
https://www.ncbi.nlm.nih.gov/pubmed/32849530
http://dx.doi.org/10.3389/fimmu.2020.01565

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