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Genetic Alterations and Transcriptional Expression of m(6)A RNA Methylation Regulators Drive a Malignant Phenotype and Have Clinical Prognostic Impact in Hepatocellular Carcinoma
Background: N6-methyladenosine (m(6)A) RNA methylation, associated with cancer initiation and progression, is dynamically regulated by the m(6)A RNA regulators. However, its role in liver carcinogenesis is poorly understood. Methods: Three hundred seventy-one hepatocellular carcinoma (HCC) patients...
Autores principales: | Zhu, Gui-Qi, Yu, Lei, Zhou, Yu-Jie, Du, Jun-Xian, Dong, Shuang-Shuang, Wu, Yi-Ming, Shi, Ying-Hong, Zhou, Jian, Fan, Jia, Dai, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396691/ https://www.ncbi.nlm.nih.gov/pubmed/32850303 http://dx.doi.org/10.3389/fonc.2020.00900 |
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