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Genetic Alterations and Transcriptional Expression of m(6)A RNA Methylation Regulators Drive a Malignant Phenotype and Have Clinical Prognostic Impact in Hepatocellular Carcinoma

Background: N6-methyladenosine (m(6)A) RNA methylation, associated with cancer initiation and progression, is dynamically regulated by the m(6)A RNA regulators. However, its role in liver carcinogenesis is poorly understood. Methods: Three hundred seventy-one hepatocellular carcinoma (HCC) patients...

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Detalles Bibliográficos
Autores principales: Zhu, Gui-Qi, Yu, Lei, Zhou, Yu-Jie, Du, Jun-Xian, Dong, Shuang-Shuang, Wu, Yi-Ming, Shi, Ying-Hong, Zhou, Jian, Fan, Jia, Dai, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396691/
https://www.ncbi.nlm.nih.gov/pubmed/32850303
http://dx.doi.org/10.3389/fonc.2020.00900

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