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Rational Design of Antigen Incorporation Into Subunit Vaccine Biomaterials Can Enhance Antigen-Specific Immune Responses

Peptide subunit vaccines increase safety by reducing the risk of off-target responses and improving the specificity of the induced adaptive immune response. The immunogenicity of most soluble peptides, however, is often insufficient to produce robust and lasting immunity. Many biomaterials and deliv...

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Detalles Bibliográficos
Autores principales: Tsoras, Alexandra N., Wong, Kong M., Paravastu, Anant K., Champion, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396695/
https://www.ncbi.nlm.nih.gov/pubmed/32849524
http://dx.doi.org/10.3389/fimmu.2020.01547