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Deregulation of Polycomb Repressive Complex-2 in Mantle Cell Lymphoma Confers Growth Advantage by Epigenetic Suppression of cdkn2b

The polycomb repressive complex 2 (PRC2) maintains the transcriptional repression of target genes through its catalytic component enhancer of zeste homolog 2 (EZH2). Through modulating critical gene expression, EZH2 also plays a role in cancer development and progression by promoting cancer cell sur...

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Detalles Bibliográficos
Autores principales:	Demosthenous, Christos, Gupta, Shiv K., Sun, Jing, Wang, Yongsen, Troska, Tammy P., Gupta, Mamta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396700/ https://www.ncbi.nlm.nih.gov/pubmed/32850364 http://dx.doi.org/10.3389/fonc.2020.01226

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