Cargando…

Persistent Pulmonary Hypertension of the Newborn: Pathophysiological Mechanisms and Novel Therapeutic Approaches

Persistent pulmonary hypertension of the newborn (PPHN) is one of the main causes of neonatal morbidity and mortality. It is characterized by sustained elevation of pulmonary vascular resistance (PVR), preventing an increase in pulmonary blood flow after birth. The affected neonates fail to establis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martinho, Sofia, Adão, Rui, Leite-Moreira, Adelino F., Brás-Silva, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396717/ https://www.ncbi.nlm.nih.gov/pubmed/32850518 http://dx.doi.org/10.3389/fped.2020.00342

Ejemplares similares

Pathophysiology, Management, and Outcome of Persistent Pulmonary Hypertension of the Newborn: A Clinical Review
por: Puthiyachirakkal, Mohammed, et al.
Publicado: (2013)

Therapeutic Approaches in Pulmonary Arterial Hypertension with Beneficial Effects on Right Ventricular Function—Preclinical Studies
por: Balsa, André, et al.
Publicado: (2023)

Diastolic ventricular function in persistent pulmonary hypertension of the newborn
por: Le Duc, Kévin, et al.
Publicado: (2023)

A Meta-Analysis of the Risk Factors of Persistent Pulmonary Hypertension in Newborns
por: Zhou, Ran, et al.
Publicado: (2021)

Heart Failure with Preserved Ejection Fraction: a Pharmacotherapeutic Update
por: Vaz-Salvador, Pedro, et al.
Publicado: (2022)

Comparison of treprostinil and oral sildenafil for the treatment of persistent pulmonary hypertension of the newborn: a retrospective cohort study
por: Wei, Enhuan, et al.
Publicado: (2023)

An Overview of Circulating Pulmonary Arterial Hypertension Biomarkers
por: Santos-Gomes, Joana, et al.
Publicado: (2022)

Role of Ion Channel Remodeling in Endothelial Dysfunction Induced by Pulmonary Arterial Hypertension
por: Santos-Gomes, Joana, et al.
Publicado: (2022)

Persistent Pulmonary Hypertension of the Newborn: The Efficacy Comparison of Vasodilators Sildenafil Plus Bosentan Versus Sildenafil Plus Beraprost at a Tertiary Childcare Health Facility
por: Adnan, Mudasser, et al.
Publicado: (2021)

Persistent pulmonary hypertension of the newborn
por: Sharma, Vinay, et al.
Publicado: (2015)

Persistent Pulmonary Hypertension in the Newborn
por: Mathew, Bobby, et al.
Publicado: (2017)

Successful Weaning From Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) After Initiation of Inhaled Epoprostenol in a Neonate With Refractory Persistent Pulmonary Hypertension of the Newborn (PPHN)
por: Shehzad, Irfan, et al.
Publicado: (2023)

NeoAPACHE II. Relationship Between Radiographic Pulmonary Area and Pulmonary Hypertension, Mortality, and Hernia Recurrence in Newborns With CDH
por: Amodeo, Ilaria, et al.
Publicado: (2021)

Mitochondrial Fission-Mediated Lung Development in Newborn Rats With Hyperoxia-Induced Bronchopulmonary Dysplasia With Pulmonary Hypertension
por: Dai, Yuanyuan, et al.
Publicado: (2021)

Patient Characteristics in Persistent Pulmonary Hypertension of the Newborn
por: Roofthooft, M. T. R., et al.
Publicado: (2011)

Risk factors for persistent pulmonary hypertension of the newborn
por: Delaney, Cassidy, et al.
Publicado: (2012)

Altered metabolites in newborns with persistent pulmonary hypertension
por: Steurer, Martina A., et al.
Publicado: (2018)

Newborn Weight Loss as a Predictor of Persistence of Exclusive Breastfeeding up to 6 Months
por: Delfino, Enrica, et al.
Publicado: (2022)

Postnatal causes and severity of persistent pulmonary Hypertension of Newborn
por: Arshad, Muhammad Sohail, et al.
Publicado: (2021)

Ambiguous Genitalia: An Unexpected Diagnosis in a Newborn
por: Losa, Ana, et al.
Publicado: (2023)

Endocrine Diseases of Newborn: Epidemiology, Pathogenesis, Therapeutic Options, and Outcome “Current Insights Into Disorders of Calcium and Phosphate in the Newborn”
por: Taylor-Miller, Tashunka, et al.
Publicado: (2021)

The Controversy Persists: Is There a Qualification Criterion to Utilize Inhaled Nitric Oxide in Pre-term Newborns?
por: Vieira, Frederico, et al.
Publicado: (2021)

A multidisciplinary approach to severe bronchopulmonary dysplasia is associated with resolution of pulmonary hypertension
por: Yung, Delphine, et al.
Publicado: (2023)

Physiologic Basis and Pathophysiologic Implications of the Diastolic Properties of the Cardiac Muscle
por: Ferreira-Martins, João, et al.
Publicado: (2010)

Molecular physiopathogenetic mechanisms and development of new potential therapeutic strategies in persistent pulmonary hypertension of the newborn
por: Distefano, Giuseppe, et al.
Publicado: (2015)

Outcome of Very Premature Newborn Receiving an Early Second Dose of Surfactant for Persistent Respiratory Distress Syndrome
por: Greiner, Eva, et al.
Publicado: (2021)

Editorial: Endocrine Diseases of Newborn: Epidemiology, Pathogenesis, Therapeutic Options and Outcome
por: Midgley, Paula Caroline, et al.
Publicado: (2021)

Use of Cranial Ultrasound Prior to the Start of Therapeutic Hypothermia for Newborn Encephalopathy
por: Alfaifi, Jaber
Publicado: (2023)

Editorial: Pediatric Pulmonary Hypertension
por: Beghetti, Maurice, et al.
Publicado: (2015)

Echocardiography in Pediatric Pulmonary Hypertension
por: Jone, Pei-Ni, et al.
Publicado: (2014)

Maternal tobacco smoke exposure and persistent pulmonary hypertension of the newborn.
por: Bearer, C, et al.
Publicado: (1997)

Risk factors and mortality among newborns with persistent pulmonary hypertension
por: Razzaq, Athar, et al.
Publicado: (2013)

The Use of Supplemental Hydrocortisone in the Management of Persistent Pulmonary Hypertension of the Newborn
por: Aleem, Samia, et al.
Publicado: (2021)

Congenital venolobar syndrome, pulmonary sequestration, and horseshoe lung in a newborn female
por: Wong, Kevin, et al.
Publicado: (2019)

Respiratory Oscillometry in Newborn Infants: Conventional and Intra-Breath Approaches
por: Radics, Bence L., et al.
Publicado: (2022)

Role of left atrial hypertension in pulmonary hypertension associated with bronchopulmonary dysplasia
por: Sullivan, Rachel T., et al.
Publicado: (2022)

The Pathophysiology of Eosinophilic Esophagitis
por: Raheem, Mayumi, et al.
Publicado: (2014)

Pathophysiology of Hyponatremia in Children
por: Zieg, Jakub
Publicado: (2017)

Pathophysiological Mechanisms of Asthma
por: Bush, Andrew
Publicado: (2019)

Congenital Adrenal Hyperplasias Presenting in the Newborn and Young Infant
por: Balsamo, Antonio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7l317c19rsj2ujogbki0bc4808