Microglia promote glioblastoma via mTOR‐mediated immunosuppression of the tumour microenvironment

Tumour‐associated microglia/macrophages (TAM) are the most numerous non‐neoplastic populations in the tumour microenvironment in glioblastoma multiforme (GBM), the most common malignant brain tumour in adulthood. The mTOR pathway, an important regulator of cell survival/proliferation, is upregulated...

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Detalles Bibliográficos
Autores principales: Dumas, Anaelle A, Pomella, Nicola, Rosser, Gabriel, Guglielmi, Loredana, Vinel, Claire, Millner, Thomas O, Rees, Jeremy, Aley, Natasha, Sheer, Denise, Wei, Jun, Marisetty, Anantha, Heimberger, Amy B, Bowman, Robert L, Brandner, Sebastian, Joyce, Johanna A, Marino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396846/
https://www.ncbi.nlm.nih.gov/pubmed/32567735
http://dx.doi.org/10.15252/embj.2019103790

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