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7-Acetoxycoumarin Inhibits LPS-Induced Inflammatory Cytokine Synthesis by IκBα Degradation and MAPK Activation in Macrophage Cells

Acetylation involves the chemical introduction of an acetyl group in place of an active hydrogen group into a compound. In this study, we synthesized 7-acetoxycoumarin (7AC) from acetylation of umbelliferone (UMB). We examined the anti-inflammatory properties of 7AC in lipopolysaccharide (LPS)-treat...

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Detalles Bibliográficos
Autores principales:	Park, Taejin, Park, Jin-Soo, Sim, Ji Han, Kim, Seung-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397006/ https://www.ncbi.nlm.nih.gov/pubmed/32650550 http://dx.doi.org/10.3390/molecules25143124

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