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Guarding the Genome: CENP-A-Chromatin in Health and Cancer

Faithful chromosome segregation is essential for the maintenance of genomic integrity and requires functional centromeres. Centromeres are epigenetically defined by the histone H3 variant, centromere protein A (CENP-A). Here we highlight current knowledge regarding CENP-A-containing chromatin struct...

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Detalles Bibliográficos
Autores principales:	Mahlke, Megan A., Nechemia-Arbely, Yael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397030/ https://www.ncbi.nlm.nih.gov/pubmed/32708729 http://dx.doi.org/10.3390/genes11070810

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