In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors

Two sets of diphenyl ether derivatives incorporating five-membered 1,3,4-oxadiazoles, and their open-chain aryl hydrazone analogs were synthesized in good yields. Most of the synthesized compounds showed promising in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv. Three di...

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Detalles Bibliográficos
Autores principales: Ibrahim, Tarek S., Taher, Ehab S., Samir, Ebtihal, M. Malebari, Azizah, Khayyat, Ahdab N., Mohamed, Mamdouh F. A., Bokhtia, Riham M., AlAwadh, Mohammed A., Seliem, Israa A., Asfour, Hani Z., Alhakamy, Nabil A., Panda, Siva S., AL-Mahmoudy, Amany M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397076/
https://www.ncbi.nlm.nih.gov/pubmed/32650556
http://dx.doi.org/10.3390/molecules25143125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397076/
https://www.ncbi.nlm.nih.gov/pubmed/32650556
http://dx.doi.org/10.3390/molecules25143125

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