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Mechanical stretching changes crosslinking and glycation levels in the collagen of mouse tail tendon

Collagen I is a major tendon protein whose polypeptide chains are linked by covalent crosslinks. It is unknown how the crosslinking contributes to the mechanical properties of tendon or whether crosslinking changes in response to stretching or relaxation. Since their discovery, imine bonds within co...

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Detalles Bibliográficos
Autores principales: Stammers, Melanie, Niewczas, Izabella S., Segonds-Pichon, Anne, Clark, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397108/
https://www.ncbi.nlm.nih.gov/pubmed/32546479
http://dx.doi.org/10.1074/jbc.RA119.012067