Cargando…

Summary of BARD1 Mutations and Precise Estimation of Breast and Ovarian Cancer Risks Associated with the Mutations

Over the last two decades, numerous BARD1 mutations/pathogenic variants (PVs) have been found in patients with breast cancer (BC) and ovarian cancer (OC). However, their role in BC and OC susceptibility remains controversial, and strong evidence-based guidelines for carriers are not yet available. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suszynska, Malwina, Kozlowski, Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397132/ https://www.ncbi.nlm.nih.gov/pubmed/32679805 http://dx.doi.org/10.3390/genes11070798

Ejemplares similares

BRIP1, RAD51C, and RAD51D mutations are associated with high susceptibility to ovarian cancer: mutation prevalence and precise risk estimates based on a pooled analysis of ~30,000 cases
por: Suszynska, Malwina, et al.
Publicado: (2020)

Do BARD1 Mutations Confer an Elevated Risk of Prostate Cancer?
por: Stempa, Klaudia, et al.
Publicado: (2021)

BARD1 is a Low/Moderate Breast Cancer Risk Gene: Evidence Based on an Association Study of the Central European p.Q564X Recurrent Mutation
por: Suszynska, Malwina, et al.
Publicado: (2019)

Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example
por: Klonowska, Katarzyna, et al.
Publicado: (2015)

Cancer predisposing BARD1 mutations in breast-ovarian cancer families
por: Ratajska, Magdalena, et al.
Publicado: (2012)

A tribute to the Bards of BEACH : Experiment Summary
por: Gibson, V
Publicado: (2014)

A synergetic effect of BARD1 mutations on tumorigenesis
por: Li, Wenjing, et al.
Publicado: (2021)

Germline mutations of BRCA1-associated RING domain (BARD1) gene in breast and/or ovarian families negative for BRCA1 and 2 alterations
por: Ghimenti, C, et al.
Publicado: (2000)

BARD1 Pathogenic Variants Are Associated with Triple-Negative Breast Cancer in a Spanish Hereditary Breast and Ovarian Cancer Cohort
por: Rofes, Paula, et al.
Publicado: (2021)

BARD1 Autoantibody Blood Test for Early Detection of Ovarian Cancer
por: Pilyugin, Maxim, et al.
Publicado: (2021)

Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers
por: Alenezi, Wejdan M., et al.
Publicado: (2020)

Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain
por: Choudhary, Rajan Kumar, et al.
Publicado: (2018)

Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer
por: Weber-Lassalle, Nana, et al.
Publicado: (2019)

The BARD1 Cys557Ser Variant and Breast Cancer Risk in Iceland
por: Stacey, Simon N, et al.
Publicado: (2006)

Performance of In Silico Prediction Tools for the Detection of Germline Copy Number Variations in Cancer Predisposition Genes in 4208 Female Index Patients with Familial Breast and Ovarian Cancer
por: Lepkes, Louisa, et al.
Publicado: (2021)

Role for a Bard1 SNP in Breast Cancer Susceptibility
por: ALONSO, Juan Manuel Fernández
Publicado: (2005)

Bioinformatics Analysis of Expression and Alterations of BARD1 in Breast Cancer
por: Chen, Yong-Zi, et al.
Publicado: (2019)

Dualistic Role of BARD1 in Cancer
por: Cimmino, Flora, et al.
Publicado: (2017)

53bp1 mutation enhances brca1 and bard1 embryonic lethality in C. elegans
por: Hariri, Sara, et al.
Publicado: (2023)

BARDES coming of age?
Publicado: (2022)

Antagonizing functions of BARD1 and its alternatively spliced variant BARD1δ in telomere stability
por: Pilyugin, Maxim, et al.
Publicado: (2016)

BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1
por: Witus, Samuel R., et al.
Publicado: (2021)

Functional consequences of a rare missense BARD1 c.403G>A germline mutation identified in a triple-negative breast cancer patient
por: Zheng, Yuanting, et al.
Publicado: (2021)

BARD1 serum autoantibodies for the detection of lung cancer
por: Pilyugin, Maxim, et al.
Publicado: (2017)

RNF19A-mediated ubiquitination of BARD1 prevents BRCA1/BARD1-dependent homologous recombination
por: Zhu, Qian, et al.
Publicado: (2021)

BARD1 mystery: tumor suppressors are cancer susceptibility genes
por: Hawsawi, Yousef M., et al.
Publicado: (2022)

Differential Expression of BARD1 Isoforms in Melanoma
por: McDougall, Lorissa I., et al.
Publicado: (2021)

BARD1 nonsense variant c.1921C>T in a patient with recurrent breast cancer
por: Gass, Jennifer, et al.
Publicado: (2017)

The Effects of Genetic and Epigenetic Alterations of BARD1 on the Development of Non-Breast and Non-Gynecological Cancers
por: Watters, Andrea K., et al.
Publicado: (2020)

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma
por: Capasso, Mario, et al.
Publicado: (2009)

Recurrent moderate‐risk mutations in Finnish breast and ovarian cancer patients
por: Nurmi, Anna, et al.
Publicado: (2019)

Clinical Response to a PARP Inhibitor and Chemotherapy in a Child with BARD1-Mutated Refractory Neuroblastoma: A Case Report
por: Cupit-Link, Maggie, et al.
Publicado: (2023)

Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells
por: Ratajczak, Mariusz Z., et al.
Publicado: (2015)

BRCA1-BARD1: the importance of being in shape
por: Daza-Martin, Manuel, et al.
Publicado: (2019)

Does it make sense to target one tumor cell chemotactic factor or its receptor when several chemotactic axes are involved in metastasis of the same cancer?
por: Ratajczak, Mariusz Z., et al.
Publicado: (2016)

Functional analysis of clinical BARD1 germline variants
por: Toh, Ming Ren, et al.
Publicado: (2019)

BARD1 Gene Polymorphisms Confer Nephroblastoma Susceptibility
por: Fu, Wen, et al.
Publicado: (2017)

BRCA Mutations Increase Fertility in Families at Hereditary Breast/Ovarian Cancer Risk
por: Kwiatkowski, Fabrice, et al.
Publicado: (2015)

Acting Shakespeare is outrageous!: playing the bard for beginners
por: Parker, Herb
Publicado: (2017)

Largest ever BARDES meeting held in Liverpool
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_56k6dpdejgiutmhv78rtpesi6t