Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples

Monolithic fillings used in chromatography are of great interest among scientists since the first reports of their synthesis and use were published. In the 20 years since silica-based monolithic columns were introduced into the commercial market, numerous papers describing their chromatographical pr...

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Detalles Bibliográficos
Autores principales: Staniak, Michał, Wójciak, Magdalena, Sowa, Ireneusz, Tyszczuk-Rotko, Katarzyna, Strzemski, Maciej, Dresler, Sławomir, Myśliński, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397265/
https://www.ncbi.nlm.nih.gov/pubmed/32660127
http://dx.doi.org/10.3390/molecules25143149
Descripción
Sumario:Monolithic fillings used in chromatography are of great interest among scientists since the first reports of their synthesis and use were published. In the 20 years since silica-based monolithic columns were introduced into the commercial market, numerous papers describing their chromatographical properties and utility in various branches of industry and scientific investigations were presented. This review is focused on possible applications of commercially available silica-based HPLC monolithic columns in the analysis of biological samples.

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