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Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples

Monolithic fillings used in chromatography are of great interest among scientists since the first reports of their synthesis and use were published. In the 20 years since silica-based monolithic columns were introduced into the commercial market, numerous papers describing their chromatographical pr...

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Autores principales: Staniak, Michał, Wójciak, Magdalena, Sowa, Ireneusz, Tyszczuk-Rotko, Katarzyna, Strzemski, Maciej, Dresler, Sławomir, Myśliński, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397265/
https://www.ncbi.nlm.nih.gov/pubmed/32660127
http://dx.doi.org/10.3390/molecules25143149
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author Staniak, Michał
Wójciak, Magdalena
Sowa, Ireneusz
Tyszczuk-Rotko, Katarzyna
Strzemski, Maciej
Dresler, Sławomir
Myśliński, Wojciech
author_facet Staniak, Michał
Wójciak, Magdalena
Sowa, Ireneusz
Tyszczuk-Rotko, Katarzyna
Strzemski, Maciej
Dresler, Sławomir
Myśliński, Wojciech
author_sort Staniak, Michał
collection PubMed
description Monolithic fillings used in chromatography are of great interest among scientists since the first reports of their synthesis and use were published. In the 20 years since silica-based monolithic columns were introduced into the commercial market, numerous papers describing their chromatographical properties and utility in various branches of industry and scientific investigations were presented. This review is focused on possible applications of commercially available silica-based HPLC monolithic columns in the analysis of biological samples.
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spelling pubmed-73972652020-08-16 Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples Staniak, Michał Wójciak, Magdalena Sowa, Ireneusz Tyszczuk-Rotko, Katarzyna Strzemski, Maciej Dresler, Sławomir Myśliński, Wojciech Molecules Review Monolithic fillings used in chromatography are of great interest among scientists since the first reports of their synthesis and use were published. In the 20 years since silica-based monolithic columns were introduced into the commercial market, numerous papers describing their chromatographical properties and utility in various branches of industry and scientific investigations were presented. This review is focused on possible applications of commercially available silica-based HPLC monolithic columns in the analysis of biological samples. MDPI 2020-07-09 /pmc/articles/PMC7397265/ /pubmed/32660127 http://dx.doi.org/10.3390/molecules25143149 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Staniak, Michał
Wójciak, Magdalena
Sowa, Ireneusz
Tyszczuk-Rotko, Katarzyna
Strzemski, Maciej
Dresler, Sławomir
Myśliński, Wojciech
Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title_full Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title_fullStr Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title_full_unstemmed Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title_short Silica-Based Monolithic Columns as a Tool in HPLC—An Overview of Application in Analysis of Active Compounds in Biological Samples
title_sort silica-based monolithic columns as a tool in hplc—an overview of application in analysis of active compounds in biological samples
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397265/
https://www.ncbi.nlm.nih.gov/pubmed/32660127
http://dx.doi.org/10.3390/molecules25143149
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