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Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions
Tumoral calcinosis involving the spine is rare. The involvement of the thoracic spine is rarer than that of the cervical or lumbar spine. We report a case of thoracic tumoral calcinosis accompanied by vertebral fracture with increased concentrations of inflammatory markers and no abnormalities in se...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397391/ https://www.ncbi.nlm.nih.gov/pubmed/32774966 http://dx.doi.org/10.1155/2020/8881698 |
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author | Miura, Isamu Kubota, Motoo Takebayashi, Kento Momosaki, Oji Honma, Koichi Kawamata, Takakazu Yuzurihara, Masahito |
author_facet | Miura, Isamu Kubota, Motoo Takebayashi, Kento Momosaki, Oji Honma, Koichi Kawamata, Takakazu Yuzurihara, Masahito |
author_sort | Miura, Isamu |
collection | PubMed |
description | Tumoral calcinosis involving the spine is rare. The involvement of the thoracic spine is rarer than that of the cervical or lumbar spine. We report a case of thoracic tumoral calcinosis accompanied by vertebral fracture with increased concentrations of inflammatory markers and no abnormalities in serum calcinosis and phosphorus concentration. A 60-year-old woman presented with complete paraplegia. Her white blood cell count and C-reactive protein (CRP) concentration were elevated. The thoracic magnetic resonance imaging revealed vertebral fracture and an epidural mass that demonstrated low intensity on both T2- and T1-weighted images at the T9/10 dorsal side of the central canal. This lesion is larger in size than that observed in the previous 2 months. Her laboratory data showed signs of infection, and only decompression surgery without fixation for treatment and diagnosis was performed. Histopathological examination was consistent with tumoral calcinosis. Postoperatively, the patient's white cell count and CRP concentration were normalized. We found that tumoral calcinosis can occur at the thoracic level on the basis of the spinal instability due to the vertebral compression fracture and the accompanying increase in inflammation indicated by increased white blood cell count and CRP concentration. |
format | Online Article Text |
id | pubmed-7397391 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-73973912020-08-07 Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions Miura, Isamu Kubota, Motoo Takebayashi, Kento Momosaki, Oji Honma, Koichi Kawamata, Takakazu Yuzurihara, Masahito Case Rep Orthop Case Report Tumoral calcinosis involving the spine is rare. The involvement of the thoracic spine is rarer than that of the cervical or lumbar spine. We report a case of thoracic tumoral calcinosis accompanied by vertebral fracture with increased concentrations of inflammatory markers and no abnormalities in serum calcinosis and phosphorus concentration. A 60-year-old woman presented with complete paraplegia. Her white blood cell count and C-reactive protein (CRP) concentration were elevated. The thoracic magnetic resonance imaging revealed vertebral fracture and an epidural mass that demonstrated low intensity on both T2- and T1-weighted images at the T9/10 dorsal side of the central canal. This lesion is larger in size than that observed in the previous 2 months. Her laboratory data showed signs of infection, and only decompression surgery without fixation for treatment and diagnosis was performed. Histopathological examination was consistent with tumoral calcinosis. Postoperatively, the patient's white cell count and CRP concentration were normalized. We found that tumoral calcinosis can occur at the thoracic level on the basis of the spinal instability due to the vertebral compression fracture and the accompanying increase in inflammation indicated by increased white blood cell count and CRP concentration. Hindawi 2020-07-24 /pmc/articles/PMC7397391/ /pubmed/32774966 http://dx.doi.org/10.1155/2020/8881698 Text en Copyright © 2020 Isamu Miura et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Miura, Isamu Kubota, Motoo Takebayashi, Kento Momosaki, Oji Honma, Koichi Kawamata, Takakazu Yuzurihara, Masahito Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title | Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title_full | Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title_fullStr | Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title_full_unstemmed | Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title_short | Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions |
title_sort | tumoral calcinosis of thoracic spine associated with vertebral fracture and inflammatory reactions |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397391/ https://www.ncbi.nlm.nih.gov/pubmed/32774966 http://dx.doi.org/10.1155/2020/8881698 |
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