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Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design

Effective chimeric antigen receptor (CAR)-T cell therapy is dependent on optimal cell culture methods conducive to the activation and expansion of T cells ex vivo, as well as infection with CAR. Media formulations used in CAR-T cell manufacturing have not been optimized for gene delivery, cell expan...

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Detalles Bibliográficos
Autores principales:	Ghassemi, Saba, Martinez-Becerra, Francisco J., Master, Alyssa M., Richman, Sarah A., Heo, David, Leferovich, John, Tu, Yitao, García-Cañaveras, Juan Carlos, Ayari, Asma, Lu, Yinan, Wang, Ai, Rabinowitz, Joshua D., Milone, Michael C., June, Carl H., O’Connor, Roddy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397397/ https://www.ncbi.nlm.nih.gov/pubmed/32775494 http://dx.doi.org/10.1016/j.omtm.2020.07.008

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