MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice

BACKGROUND & AIMS: Intestinal epithelial homeostasis depends on a tightly regulated balance between intestinal epithelial cell (IEC) death and proliferation. While the disruption of several IEC death regulating factors result in intestinal inflammation, the loss of the anti-apoptotic BCL2 family...

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Detalles Bibliográficos
Autores principales: Healy, Marc E., Boege, Yannick, Hodder, Michael C., Böhm, Friederike, Malehmir, Mohsen, Scherr, Anna-Lena, Jetzer, Jasna, Chan, Lap Kwan, Parrotta, Rossella, Jacobs, Kurt, Clerbaux, Laure-Alix, Kreutzer, Susanne, Campbell, Andrew, Gilchrist, Ella, Gilroy, Kathryn, Rodewald, Ann-Katrin, Honcharova-Biletska, Hanna, Schimmer, Roman, Vélez, Karelia, Büeler, Simone, Cammareri, Patrizia, Kalna, Gabriela, Wenning, Anna S., McCoy, Kathy D., Gomez de Agüero, Mercedes, Schulze-Bergkamen, Henning, Klose, Christoph S.N., Unger, Kristian, Macpherson, Andrew J., Moor, Andreas E., Köhler, Bruno, Sansom, Owen J., Heikenwälder, Mathias, Weber, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397524/
https://www.ncbi.nlm.nih.gov/pubmed/32179094
http://dx.doi.org/10.1053/j.gastro.2020.03.017

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