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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
BACKGROUND: Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeutic potentials. Beta2 microglobulin (B2M) and MHC II trans...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397609/ https://www.ncbi.nlm.nih.gov/pubmed/32746912 http://dx.doi.org/10.1186/s13287-020-01847-9 |