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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey

BACKGROUND: Stem cells, including induced pluripotent stem cells (iPSCs), have tremendous potential in health care, though with several significant limitations. Each of the limitations, including immunogenicity, may block most of the therapeutic potentials. Beta2 microglobulin (B2M) and MHC II trans...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaokai, Lu, Meng, Tian, Xiaoyu, Ren, Yansong, Li, Yijun, Xiang, Meng, Chen, Sifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397609/ https://www.ncbi.nlm.nih.gov/pubmed/32746912 http://dx.doi.org/10.1186/s13287-020-01847-9

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