Tolerability and efficacy of vortioxetine versus SSRIs in elderly with major depression. Study protocol of the VESPA study: a pragmatic, multicentre, open-label, parallel-group, superiority, randomized trial

INTRODUCTION: Depression is a highly prevalent condition in the elderly, with a vast impact on quality of life, life expectancy, and medical outcomes. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed agents in this condition and, although generally safe, tolerability...

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Detalles Bibliográficos
Autores principales: Ostuzzi, Giovanni, Gastaldon, Chiara, Barbato, Angelo, D’Avanzo, Barbara, Tettamanti, Mauro, Monti, Igor, Aguglia, Andrea, Aguglia, Eugenio, Alessi, Maria Chiara, Amore, Mario, Bartoli, Francesco, Biondi, Massimo, Bortolaso, Paola, Callegari, Camilla, Carrà, Giuseppe, Caruso, Rosangela, Cavallotti, Simone, Crocamo, Cristina, D’Agostino, Armando, De Fazio, Pasquale, Di Natale, Chiara, Giusti, Laura, Grassi, Luigi, Martinotti, Giovanni, Nosé, Michela, Papola, Davide, Purgato, Marianna, Rodolico, Alessandro, Roncone, Rita, Tarsitani, Lorenzo, Turrini, Giulia, Zanini, Elisa, Amaddeo, Francesco, Ruggeri, Mirella, Barbui, Corrado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397635/
https://www.ncbi.nlm.nih.gov/pubmed/32746941
http://dx.doi.org/10.1186/s13063-020-04460-6

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