Role of platelet biomarkers in inflammatory response

Beyond hemostasis, thrombosis and wound healing, it is becoming increasingly clear that platelets play an integral role in inflammatory response and immune regulation. Platelets recognize pathogenic microorganisms and secrete various immunoregulatory cytokines and chemokines, thus facilitating a var...

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Autores principales: Chen, Yufei, Zhong, Haoxuan, Zhao, Yikai, Luo, Xinping, Gao, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397646/
https://www.ncbi.nlm.nih.gov/pubmed/32774856
http://dx.doi.org/10.1186/s40364-020-00207-2
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author Chen, Yufei
Zhong, Haoxuan
Zhao, Yikai
Luo, Xinping
Gao, Wen
author_facet Chen, Yufei
Zhong, Haoxuan
Zhao, Yikai
Luo, Xinping
Gao, Wen
author_sort Chen, Yufei
collection PubMed
description Beyond hemostasis, thrombosis and wound healing, it is becoming increasingly clear that platelets play an integral role in inflammatory response and immune regulation. Platelets recognize pathogenic microorganisms and secrete various immunoregulatory cytokines and chemokines, thus facilitating a variety of immune effects and regulatory functions. In this review, we discuss recent advances in signaling of platelet activation-related biomarkers in inflammatory settings and application prospects to apply for disease diagnosis and treatment.
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spelling pubmed-73976462020-08-06 Role of platelet biomarkers in inflammatory response Chen, Yufei Zhong, Haoxuan Zhao, Yikai Luo, Xinping Gao, Wen Biomark Res Review Beyond hemostasis, thrombosis and wound healing, it is becoming increasingly clear that platelets play an integral role in inflammatory response and immune regulation. Platelets recognize pathogenic microorganisms and secrete various immunoregulatory cytokines and chemokines, thus facilitating a variety of immune effects and regulatory functions. In this review, we discuss recent advances in signaling of platelet activation-related biomarkers in inflammatory settings and application prospects to apply for disease diagnosis and treatment. BioMed Central 2020-08-02 /pmc/articles/PMC7397646/ /pubmed/32774856 http://dx.doi.org/10.1186/s40364-020-00207-2 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Chen, Yufei
Zhong, Haoxuan
Zhao, Yikai
Luo, Xinping
Gao, Wen
Role of platelet biomarkers in inflammatory response
title Role of platelet biomarkers in inflammatory response
title_full Role of platelet biomarkers in inflammatory response
title_fullStr Role of platelet biomarkers in inflammatory response
title_full_unstemmed Role of platelet biomarkers in inflammatory response
title_short Role of platelet biomarkers in inflammatory response
title_sort role of platelet biomarkers in inflammatory response
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397646/
https://www.ncbi.nlm.nih.gov/pubmed/32774856
http://dx.doi.org/10.1186/s40364-020-00207-2
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AT luoxinping roleofplateletbiomarkersininflammatoryresponse
AT gaowen roleofplateletbiomarkersininflammatoryresponse

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