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Stochiometric quantification of the thiol redox proteome of macrophages reveals subcellular compartmentalization and susceptibility to oxidative perturbations
Posttranslational modifications of protein cysteine thiols play a significant role in redox regulation and the pathogenesis of human diseases. Herein, we report the characterization of the cellular redox landscape in terms of quantitative, site-specific occupancies of both S-glutathionylation (SSG)...
Autores principales: | Duan, Jicheng, Zhang, Tong, Gaffrey, Matthew J., Weitz, Karl K., Moore, Ronald J., Li, Xiaolu, Xian, Ming, Thrall, Brian D., Qian, Wei-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397701/ https://www.ncbi.nlm.nih.gov/pubmed/32750668 http://dx.doi.org/10.1016/j.redox.2020.101649 |
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